Is gene therapy for hypertension possible?
نویسنده
چکیده
45. Wu P, Phillips MI, Bui J, Terilliger EF. Adeno-associated viral vector mediated transgene integration in nondividing cells. J Virol. 1998;72:
منابع مشابه
An Enterovirus-Like RNA Construct for Colon Cancer Suicide Gene Therapy
Background: In gene therapy, the use of RNA molecules as therapeutic agents has shown advantages over plasmid DNA, including higher levels of safety. However, transient nature of RNA has been a major obstacle in application of RNA in gene therapy. Methods: Here, we used the internal ribosomal entry site of encephalomyocarditis virus and the 3’ non-translated region of Poliovirus to design an en...
متن کاملEffectiveness of Compassion-Focused Therapy on Blood Pressure and Quality of Life in Women with Hypertension
Introduction: Due to the increasing prevalence of patients with hypertension in Iran and the world as well as the adverse impact of this disease on quality of life, there is an urgent need to develop effective and empirically supported psychological interventions in this population. This study aimed to evaluate the effectiveness of compassion-focused therapy on blood pressure and the quality of...
متن کاملRiboflavin Lowers Blood Pressure: A Review of a Novel Gene-nutrient Interaction
Hypertension, defined as a systolic/diastolic blood pressure of 140/90 mmHg or greater, is estimated to carry a three-fold increased risk of developing cardiovascular diseases (CVDs). Evidence from genome-wide association studies has identified an association between blood pressure and the gene encoding the folate-metabolising enzyme, methylenetetrahydrofolate reductase (MTHFR). Recent meta-ana...
متن کاملنگاهی به ژن درمانی، پیشرفتهای اخیر و چشم انداز آینده
Human gene therapy has attracted increasing attention as a highly encouraging therapeutic approach to treat wide variety of diseases, other than genetically inherited and monogenic disorders. This approach entails the introduction and expression of a variety of nucleic acids into human target cells for therapeutic purposes. In this article, we review the history, highlights, recently progresses...
متن کاملThe Role of Gene Therapy in Cartilage Repair
The key principle of gene delivery to articulations by direct intra-articular injection is to release complementary DNA(cDNA)-encoding medical products that will lead to maintained, endogenous production of the gene products withinthe articulation. In fact, this has been accomplished for both in vivo and ex vivo gene delivery, using several vectors,genes, and cells in some animal models. Some c...
متن کاملمبانی فقهی ـ حقوقی مشروعیت ژن‌درمانی در ادیان توحیدی
Religious scholars were among the first to address the challenges of genetic science. In this regard, religious institutions from the beginning has debate on moral and religious challenges of gene therapy. Because public acceptance towards gene therapy is largely rooted in religious beliefs, Religious doctrine undoubtedly play a key role in shaping public attitudes and policy about gene therapy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Hypertension
دوره 33 1 شماره
صفحات -
تاریخ انتشار 1999